CADM1 and HYOU1

Data Source:
BioGRID (affinity chromatography technology)

		CADM1	HYOU1
Description		cell adhesion molecule 1	hypoxia up-regulated 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Synapse	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Endoplasmic Reticulum Chaperone Complex Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity	Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Positive Regulation Of Cytokine Production T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organism Development Spermatogenesis Cell Recognition Viral Process Cell Differentiation Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Activated T Cell Proliferation Detection Of Stimulus	Response To Ischemia Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Regulation Of Catalytic Activity Cellular Response To Hypoxia Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	Scavenging by Class F Receptors Scavenging by Class F Receptors XBP1(S) activates chaperone genes
Drugs
Diseases		Nasopharyngeal cancer
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 31308545) Body mass index ( 28552196 31978080 28892062 25673413) Body size at age 10 ( 32376654) Cardiovascular risk factors (age interaction) ( 20838585) Childhood body mass index ( 33045005) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798 32041948) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 30598549 28869591) Left-handedness ( 32989287) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Thyroid stimulating hormone levels ( 30367059 32769997) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)	Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		7 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 MPP3 PSMA6 SDCBP	3 interacting genes: CDC42 LINC01554 SEL1L
Entrez ID		23705	10525
HPRD ID		05746	03448
Ensembl ID		ENSG00000182985	ENSG00000149428
Uniprot IDs		A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5	A0A384P5T6 A0A494C039 B3KXH0 B7Z602 B7Z766 Q6IN67 Q9Y4L1
PDB IDs		3BIN 4H5S
Enriched GO Terms of Interacting Partners?
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