KCNE4 and CAMLG

Data Source:
BioGRID (two hybrid)

		KCNE4	CAMLG
Description		potassium voltage-gated channel subfamily E regulatory subunit 4	calcium modulating ligand
Image		No pdb structure
GO Annotations	Cellular Component	Voltage-gated Potassium Channel Complex Apical Plasma Membrane	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Delayed Rectifier Potassium Channel Activity	Defense Response Signal Transduction Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization
Pathways		Phase 3 - rapid repolarisation Phase 2 - plateau phase	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Enflurane Promethazine Miconazole	Cyclosporine
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 19684603) Body mass index ( 20966902) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Logical memory (delayed recall) in normal cognition ( 29274321) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Waist circumference ( 20966902) Weight ( 28552196)	Height ( 18391951)
Interacting Genes		10 interacting genes: CAMLG FLNA GET3 KCNA1 KCNQ1 OBSL1 PRKCA TCF7L2 TRDN TSNAX	22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB RPN1 TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		23704	819
HPRD ID		09689	03073
Ensembl ID			ENSG00000164615
Uniprot IDs		A5H1P5 Q8WWG9	P49069
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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