LSM5 and TBPL1

Data Source:
BioGRID (two hybrid)

		LSM5	TBPL1
Description		LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated	TATA-box binding protein like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	RNA Binding Protein Binding Protein Heterodimerization Activity	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity General Transcription Initiation Factor Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process Response To Bacterium Exonucleolytic Catabolism Of Deadenylated MRNA	Acrosome Assembly DTTP Biosynthetic Process DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Spermatid Nucleus Differentiation
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971) Extremely high intelligence ( 29520040) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Morning person ( 30696823) Palmitic acid (16:0) levels ( 23362303) Smooth-surface caries ( 24556642)	Height ( 28552196) Night sleep phenotypes ( 27126917)
Interacting Genes		16 interacting genes: DDIT4L EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 PLK3 SMN1 SNRPE SNRPF TBPL1 TCL1B TEX43	18 interacting genes: ABCF3 APP DVL3 FBXO7 GTF2A1 GTF2A2 GTF2B IRAK4 LSM5 NDUFA6 NF1 PLIN3 PRNP PTCD3 RAB35 RPL10 SLC35F6 TNNT1
Entrez ID		23658	9519
HPRD ID		06285	09272
Ensembl ID		ENSG00000106355	ENSG00000028839
Uniprot IDs		A0A090N8Y5 Q9Y4Y9	P62380
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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