TBPL1 and RPL10

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBPL1	RPL10
Description		TATA-box binding protein like 1	ribosomal protein L10
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity General Transcription Initiation Factor Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity
	Biological Process	Acrosome Assembly DTTP Biosynthetic Process DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Spermatid Nucleus Differentiation	Ribosomal Large Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Negative Regulation Of Apoptotic Process Embryonic Brain Development
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS		Height ( 28552196) Night sleep phenotypes ( 27126917)
Interacting Genes		18 interacting genes: ABCF3 APP DVL3 FBXO7 GTF2A1 GTF2A2 GTF2B IRAK4 LSM5 NDUFA6 NF1 PLIN3 PRNP PTCD3 RAB35 RPL10 SLC35F6 TNNT1	14 interacting genes: DUX4 ERCC6 FYN HCK LYN MAPK6 PRKCA PTEN RAD21 SRC SUMO2 TAB1 TBPL1 YES1
Entrez ID		9519	6134
HPRD ID		09272	02421
Ensembl ID		ENSG00000028839	ENSG00000147403
Uniprot IDs		P62380	A0A087WV22 P27635 X5D2T3
PDB IDs			2PA2 5AJ0 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6W6L
Enriched GO Terms of Interacting Partners?
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