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EDC4 and MIR34A
Data Source:
BioGRID
(unspecified method)
EDC4
MIR34A
Description
enhancer of mRNA decapping 4
microRNA 34a
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Cytoplasmic Ribonucleoprotein Granule
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Protein Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Biological_process
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Exonucleolytic Catabolism Of Deadenylated MRNA
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Pathways
mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
HDL cholesterol (
21347282
)
Metabolic syndrome (
22399527
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Height (
31562340
)
Lean body mass (
28552196
)
Interacting Genes
38 interacting genes:
CCL5
CDC42
EIF2AK2
FBLN1
GIT2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR122
MIR128-2
MIR141
MIR15B
MIR199A1
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR21
MIR214
MIR222
MIR29C
MIR34A
MIR34C
MIR363
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A3
MIRLET7C
MIRLET7D
MIRLET7E
SUMO2
YTHDC1
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
Entrez ID
23644
407040
HPRD ID
06911
Ensembl ID
ENSG00000038358
ENSG00000284357
Uniprot IDs
Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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