EDC4 and MIR200B

Data Source:
BioGRID (unspecified method)

		EDC4	MIR200B
Description		enhancer of mRNA decapping 4	microRNA 200b
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Catabolism Of Deadenylated MRNA	Positive Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Negative Regulation Of Angiogenesis Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Vascular Wound Healing Positive Regulation Of Cell Cycle Arrest Negative Regulation Of Interleukin-33 Production Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways		mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		38 interacting genes: CCL5 CDC42 EIF2AK2 FBLN1 GIT2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR122 MIR128-2 MIR141 MIR15B MIR199A1 MIR200A MIR200B MIR200C MIR205 MIR20A MIR21 MIR214 MIR222 MIR29C MIR34A MIR34C MIR363 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E SUMO2 YTHDC1	83 interacting genes: ADARB1 APOBEC3B AQR C1QBP CDC5L CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		23644	406984
HPRD ID		06911
Ensembl ID		ENSG00000038358	ENSG00000207730
Uniprot IDs		Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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