ZMYND8 and ZFYVE9

Data Source:
HPRD (two hybrid)

		ZMYND8	ZFYVE9
Description		zinc finger MYND-type containing 8	zinc finger FYVE-type containing 9
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Dendritic Spine Dendritic Shaft	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Methylated Histone Binding Protein N-terminus Binding Repressing Transcription Factor Binding Lysine-acetylated Histone Binding	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Migration Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Dendritic Spine Maintenance	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Migraine ( 27182965) Parahippocampal gyrus volume ( 31530798) Platelet distribution width ( 32888494) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: ATN1 CSNK1E ERBB2 FHOD1 H3C1 MEOX2 PBXIP1 PRKCB RERE SPOP SUMO2 USP7 ZBTB7A ZFYVE9	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		23613	9372
HPRD ID		10166	04782
Ensembl ID		ENSG00000101040	ENSG00000157077
Uniprot IDs		A0A087WVZ6 A6H8Y8 Q2HXV5 Q569J9 Q9ULU4	O95405
PDB IDs		4COS 5B73 5MQ4 5Y1Z	1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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