RHOBTB2 and RHOBTB3

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RHOBTB2	RHOBTB3
Description		Rho related BTB domain containing 2	Rho related BTB domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Trans-Golgi Network Membrane Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	GTPase Activity Protein Binding ATP Binding GTP Binding ATPase Activity Protein Kinase Binding Small GTPase Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Engulfment Of Apoptotic Cell Regulation Of Small GTPase Mediated Signal Transduction	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Regulation Of Cell Shape Male Gonad Development Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Retrograde Transport, Endosome To Golgi
Pathways		RHOBTB2 GTPase cycle	Retrograde transport at the Trans-Golgi-Network RHOBTB3 ATPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Height ( 28552196) Plasma trimethylamine N-oxide levels ( 28439531) Renal cell carcinoma ( 28598434) Survival in breast cancer (estrogen-receptor positive) ( 29423119)
Interacting Genes		12 interacting genes: BAG4 CHEK2 CUL5 ERBB2 FGFR2 HSP90AA1 HSP90AB1 PALB2 PPM1D PTPN1 RHOBTB3 STK11	17 interacting genes: BHLHE40 CCNE1 CUL3 EFHC2 HGS IHO1 L3MBTL3 PLAGL2 RAB9A RBPMS RBX1 RHOBTB2 TBX15 UBXN11 USP54 VHL ZRANB1
Entrez ID		23221	22836
HPRD ID		06300	09557
Ensembl ID		ENSG00000008853	ENSG00000164292
Uniprot IDs		Q9BYZ6	O94955
PDB IDs
Enriched GO Terms of Interacting Partners?
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