MAPK8IP3 and RIC8A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAPK8IP3	RIC8A
Description		mitogen-activated protein kinase 8 interacting protein 3	RIC8 guanine nucleotide exchange factor A
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm	Cytoplasm Plasma Membrane
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Signaling Receptor Complex Adaptor Activity	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Activation Of JUN Kinase Activity Vesicle-mediated Transport Axon Regeneration Regulation Of JNK Cascade Axon Development Anterograde Axonal Protein Transport	In Utero Embryonic Development Vasculature Development G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Visual Learning Cell Migration Involved In Gastrulation Positive Regulation Of GTPase Activity Cell-cell Adhesion Involved In Gastrulation Basement Membrane Organization
Pathways
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Cataracts (operation) ( 31816047) Gynecologic disease ( 31488892) Gynecologic disease (multivariate analysis) ( 31488892) Mean corpuscular hemoglobin concentration ( 29403010) Meningioma ( 29762745) Platelet count ( 24026423) Uterine fibroids ( 21460842 31488892 31649266) Uterine fibroids (MTAG) ( 31488892)
Interacting Genes		26 interacting genes: ARL4D CASP3 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 PTK2 RAD51 RAD51D RAF1 RIC8A SRC SULT4A1 TLR2 TLR4 TLR9 ZNF575	24 interacting genes: ATP1A4 EFEMP1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS MAPK8IP3 NECAB2 NUTM1 PACSIN2 RABAC1 SDCBP SH3GLB1 SLC2A13 TERF1 TUBB2A UBQLN1 UBQLN4 XPO1 ZDHHC17 ZNF585B
Entrez ID		23162	60626
HPRD ID		12014	12373
Ensembl ID		ENSG00000138834	ENSG00000177963
Uniprot IDs		A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6	Q9NPQ8
PDB IDs		4PXJ
Enriched GO Terms of Interacting Partners?
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