SEPTIN6 and S100A4

Data Source:
HPRD (in vitro)

		SEPTIN6	S100A4
Description		septin 6	S100 calcium binding protein A4
Image
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Mitotic Cytokinesis Spermatogenesis Viral Process Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs			Trifluoperazine Copper
Diseases
GWAS			Blood protein levels ( 29875488) Pulse pressure ( 30578418)
Interacting Genes		14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1	28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		23157	6275
HPRD ID		06716	15914
Ensembl ID		ENSG00000125354	ENSG00000196154
Uniprot IDs		B1AMS2 Q14141 Q541S4 Q548C9	P26447
PDB IDs		2QAG 6UPA	1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58
Enriched GO Terms of Interacting Partners?
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