SEPTIN6 and NSD3

Data Source:
BioGRID (two hybrid)

		SEPTIN6	NSD3
Description		septin 6	nuclear receptor binding SET domain protein 3
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GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus	Chromatin Nucleus Nucleoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Mitotic Cytokinesis Spermatogenesis Viral Process Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1	42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		23157	54904
HPRD ID		06716	06155
Ensembl ID		ENSG00000125354	ENSG00000147548
Uniprot IDs		B1AMS2 Q14141 Q541S4 Q548C9	Q9BZ95
PDB IDs		2QAG 6UPA	2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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