CIC and SEC62

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CIC	SEC62
Description		capicua transcriptional repressor	SEC62 homolog, preprotein translocation factor
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	Signaling Receptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated	Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Posttranslational Protein Targeting To Membrane, Translocation
Pathways
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Neutrophil count ( 32888494)	Cadmium levels ( 26025379)
Interacting Genes		13 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GOLGA2 GTPBP3 NFYC PICK1 POLR1H PYCR2 SEC62 SETD2 TRIM22	4 interacting genes: CIC GABARAP SEC63 ZNF24
Entrez ID		23152	7095
HPRD ID		10831	03706
Ensembl ID		ENSG00000079432	ENSG00000008952
Uniprot IDs		A0A0A0MQR4 Q96RK0	D3DNQ1 Q99442
PDB IDs		2M41 4J2J 4J2L 6JRP 6KZG 6KZH	7BRT
Enriched GO Terms of Interacting Partners?
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