SEC62 and SEC63

Data Source:
HPRD (in vitro)

		SEC62	SEC63
Description		SEC62 homolog, preprotein translocation factor	SEC63 homolog, protein translocation regulator
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Sec62/Sec63 Complex
	Molecular Function	Signaling Receptor Activity	RNA Binding Protein Binding Protein Transmembrane Transporter Activity Signaling Receptor Activity
	Biological Process	Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Posttranslational Protein Targeting To Membrane, Translocation	Liver Development Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Nitrogen Compound Metabolic Process Multicellular Organism Aging Posttranslational Protein Targeting To Membrane, Translocation
Pathways
Drugs
Diseases			Polycystic liver disease
GWAS		Cadmium levels ( 26025379)	Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction ( 32080893)
Interacting Genes		4 interacting genes: CIC GABARAP SEC63 ZNF24	4 interacting genes: HSPA5 MEOX2 SEC61B SEC62
Entrez ID		7095	11231
HPRD ID		03706	09783
Ensembl ID		ENSG00000008952	ENSG00000025796
Uniprot IDs		D3DNQ1 Q99442	A0A0S2Z5M1 Q9UGP8
PDB IDs		7BRT
Enriched GO Terms of Interacting Partners?
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