MAST2 and CDHR2

Data Source:
HPRD (in vivo, two hybrid)

		MAST2	CDHR2
Description		microtubule associated serine/threonine kinase 2	cadherin related family member 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Microtubule Cytoskeleton	Brush Border Apical Plasma Membrane Cell Junction Brush Border Membrane Microvillus Membrane Spanning Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Calcium Ion Binding Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Peptidyl-serine Phosphorylation Regulation Of Interleukin-12 Production Intracellular Signal Transduction Spermatid Differentiation	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Epithelial Cell Differentiation Regulation Of Microvillus Length Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Cell Growth Involved In Contact Inhibition Intermicrovillar Adhesion Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Granulocyte count ( 27863252) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Sum basophil neutrophil counts ( 27863252) Type 2 diabetes ( 32499647)	Height ( 28552196)
Interacting Genes		24 interacting genes: ACTN2 APP CDHR2 DYNLL1 MXRA7 PTEN RPS27A RPS6KA1 SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 SRPK2 STK36 SUMO2 TK1 TPM1 TPM2 TPM3 TRAF2 TRAF6 TTN ZNF417	1 interacting genes: MAST2
Entrez ID		23139	54825
HPRD ID		11294	15103
Ensembl ID		ENSG00000086015	ENSG00000074276
Uniprot IDs		A0A669KBJ4 Q6P0Q8	Q9BYE9
PDB IDs		2KQF 2KYL	5CZR
Enriched GO Terms of Interacting Partners?
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