USP33 and CCP110

Data Source:
BioGRID (enzymatic study)

		USP33	CCP110
Description		ubiquitin specific peptidase 33	centriolar coiled-coil protein 110
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Focal Adhesion VCB Complex Cell Body Perinuclear Region Of Cytoplasm	Centrosome Centriole Cytosol Cilium Protein-containing Complex
	Molecular Function	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Small GTPase Binding Ubiquitin Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Axon Guidance Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Autophagy Cell Migration Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Protein Stabilization Centrosome Duplication Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	G2/M Transition Of Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of Cilium Assembly Negative Regulation Of Centriole Elongation
Pathways		Ub-specific processing proteases Regulation of expression of SLITs and ROBOs	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2
Drugs
Diseases
GWAS		Adult body size ( 32376654) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		14 interacting genes: CCP110 CHRM5 DDX56 DIO2 EIF6 ELOC SELENBP1 TRIM54 TRIM63 UBC USP15 USP21 USP28 VHL	13 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 PCNT PNMA1 TFIP11 USP33
Entrez ID		23032	9738
HPRD ID		10297	10848
Ensembl ID		ENSG00000077254	ENSG00000103540
Uniprot IDs		Q8TEY7	O43303
PDB IDs		2UZG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?