RPIA and VTA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPIA	VTA1
Description		ribose 5-phosphate isomerase A	vesicle trafficking 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Ribose-5-phosphate Isomerase Activity Protein Binding Identical Protein Binding Monosaccharide Binding	Protein Binding Protein C-terminus Binding
	Biological Process	D-ribose Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Ribose Phosphate Metabolic Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways		RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs		4-phospho-L-threonic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863)
Interacting Genes		19 interacting genes: ATPAF2 C14orf119 CENPP DDIT4L FOXP2 FXR2 GORASP2 HSPB8 LNX1 NIF3L1 NTAQ1 PCMT1 PICK1 PTPN11 RNF208 SDCBP STK16 TXN2 VTA1	22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2
Entrez ID		22934	51534
HPRD ID		01589	09855
Ensembl ID		ENSG00000153574	ENSG00000009844
Uniprot IDs		P49247	A0A087WY55 Q9NP79
PDB IDs			2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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