MAPRE3 and TRAIP

Data Source:
BioGRID (two hybrid)

		MAPRE3	TRAIP
Description		microtubule associated protein RP/EB family member 3	TRAF interacting protein
Image
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End	Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm Site Of DNA Damage
	Molecular Function	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end	Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Replication Fork Processing Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production Protein-DNA Covalent Cross-linking Repair
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077)
Interacting Genes		60 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 C4orf45 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GAS2L2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE1 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B TAOK2 TEX43 TLE5 TRAIP TRIM14 TROAP TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547	28 interacting genes: ALOX15B APP CEP19 CYLD FLII LXN MAGEF1 MAPRE2 MAPRE3 POLK POLR1C RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2
Entrez ID		22924	10293
HPRD ID		16156	05811
Ensembl ID		ENSG00000084764	ENSG00000183763
Uniprot IDs		Q9UPY8	Q9BWF2
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7	4ZTD
Enriched GO Terms of Interacting Partners?
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