CLCA4 and THAP4

Data Source:
BioGRID (two hybrid)

		CLCA4	THAP4
Description		chloride channel accessory 4	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane	Cellular_component
	Molecular Function	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Metallopeptidase Activity Metal Ion Binding	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	Proteolysis Ion Transmembrane Transport Chloride Transmembrane Transport	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS			Brain structure ( 20171287) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		23 interacting genes: AQP2 BDKRB2 ELOVL4 ERGIC3 FAM209A FCER1G FKBP7 GPR42 LMNA MCFD2 MGST3 PANX1 RETREG3 SCN3B SLC22A23 SLC35E2A SLC39A2 SLC39A7 SPN THAP4 TMEM154 TMEM179B TMEM51	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		22802	51078
HPRD ID		16719	11630
Ensembl ID		ENSG00000016602	ENSG00000176946
Uniprot IDs		Q14CN2	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?
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