FHL1 and PAX7

Data Source:
BioGRID (two hybrid)

		FHL1	PAX7
Description		four and a half LIM domains 1	paired box 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Chromatin Nucleus
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Anatomical Structure Morphogenesis Negative Regulation Of Apoptotic Process Anatomical Structure Development
Pathways
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy	Alveolar rhabdomyosarcoma
GWAS			Body mass index ( 23669352) Cleft lip with or without cleft palate ( 28054174) Cortical surface area (visual PC2) ( 32198502) Knee osteoarthritis ( 28916551) Nonsyndromic cleft lip with cleft palate ( 28232668) Orofacial clefts ( 22863734 28054174) Percentage gas trapping ( 26030696) Response to amphetamines ( 22952603) Urate levels in lean individuals ( 25811787)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	11 interacting genes: C1orf109 CIB1 CSNK2A1 CT55 FHL1 HIRA HOMER3 KRTAP19-7 MAGOHB NEDD4 TCAP
Entrez ID		2273	5081
HPRD ID		02157	01331
Ensembl ID		ENSG00000022267	ENSG00000009709
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	P23759
PDB IDs		1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?
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