FHL1 and LAMA4

Data Source:
BioGRID (two hybrid)

		FHL1	LAMA4
Description		four and a half LIM domains 1	laminin subunit alpha 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cell Adhesion Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Regulation Of Embryonic Development Negative Regulation Of Cold-induced Thermogenesis
Pathways			Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans MET activates PTK2 signaling
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS			Bipolar disorder ( 31043756) Metabolite levels ( 23823483)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	17 interacting genes: APC ATF7IP BRD7 COPS6 EEF1A1 FHL1 GAPDH LRIF1 MED31 PTN RTN4 RTP2 TP53 TUBB2A UBR1 UNC119 ZHX1
Entrez ID		2273	3910
HPRD ID		02157	02532
Ensembl ID		ENSG00000022267	ENSG00000112769
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	A0A0A0MQS9 A0A0A0MTC7 Q16363 Q5D044
PDB IDs		1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?
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