MAPK15 and TGFB1I1

Data Source:
HPRD (in vivo)

		MAPK15	TGFB1I1
Description		mitogen-activated protein kinase 15	transforming growth factor beta 1 induced transcript 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Autophagosome Golgi Apparatus Centriole Cell-cell Junction Bicellular Tight Junction Axoneme Cytoplasmic Vesicle Ciliary Basal Body Meiotic Spindle	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Chromatin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity SH3 Domain Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding
	Biological Process	MAPK Cascade Regulation Of COPII Vesicle Coating Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Organization Positive Regulation Of Cell Population Proliferation Regulation Of Autophagy Negative Regulation Of Cell Migration Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Dopamine Uptake Regulation Of Cilium Assembly Positive Regulation Of Telomere Capping Protein Localization To Ciliary Transition Zone Positive Regulation Of Metaphase/anaphase Transition Of Meiosis I Positive Regulation Of Spindle Assembly	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs		Acetylsalicylic acid Minocycline Fostamatinib
Diseases
GWAS		Obesity-related traits ( 23251661)	Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 SRC TGFB1I1	29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL
Entrez ID		225689	7041
HPRD ID		16867	03831
Ensembl ID		ENSG00000181085	ENSG00000140682
Uniprot IDs		Q8TD08	A0A024QZE7 O43294
PDB IDs
Enriched GO Terms of Interacting Partners?
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