TGFB1I1 and GP1BB

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TGFB1I1	GP1BB
Description		transforming growth factor beta 1 induced transcript 1	glycoprotein Ib platelet subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation
Pathways			Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) Defective F9 activation
Drugs
Diseases			Bernard-Soulier syndrome; Giant platelet syndrome
GWAS		Metabolite levels ( 23823483)	DNA methylation (parent-of-origin) ( 23725790) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252)
Interacting Genes		29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	4 interacting genes: GP9 PRKACA TGFB1I1 YWHAZ
Entrez ID		7041	2812
HPRD ID		03831	00729
Ensembl ID		ENSG00000140682	ENSG00000203618
Uniprot IDs		A0A024QZE7 O43294	P13224
PDB IDs			3REZ 3RFE
Enriched GO Terms of Interacting Partners?
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