ZSCAN23 and TULP3

Data Source:
BioGRID (two hybrid)

		ZSCAN23	TULP3
Description		zinc finger and SCAN domain containing 23	TUB like protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Nucleus Nucleoplasm Nucleolus Plasma Membrane Cilium Axoneme Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Neural Tube Closure Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Anterior/posterior Pattern Specification Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways			Hedgehog 'off' state
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Fish- and plant-related diet ( 32066663) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 28991256) Subcortical volume (MOSTest) ( 32665545)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		22 interacting genes: BICD2 CCDC130 CDR2L CEP70 DDIT4L GOLGA6L9 LHPP PCDHB12 PICK1 PPARA PRKAA2 SCAND1 SDCBP TRAF2 TULP3 ZKSCAN7 ZNF24 ZNF426 ZNF446 ZSCAN21 ZSCAN22 ZSCAN9	63 interacting genes: ACTN2 AKAP9 ANKRD1 ANKRD54 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PRKAR1A PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23
Entrez ID		222696	7289
HPRD ID		19514	05292
Ensembl ID		ENSG00000187987	ENSG00000078246
Uniprot IDs		Q3MJ62	B7Z1E7 O75386
PDB IDs
Enriched GO Terms of Interacting Partners?
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