TULP3 and MYO18B

Data Source:
BioGRID (two hybrid)

		TULP3	MYO18B
Description		TUB like protein 3	myosin XVIIIB
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Plasma Membrane Cilium Axoneme Ciliary Base 9+0 Non-motile Cilium	Nucleus Unconventional Myosin Complex Z Disc Filamentous Actin
	Molecular Function	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding	Motor Activity Actin Binding ATP Binding
	Biological Process	Neural Tube Closure Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Anterior/posterior Pattern Specification Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning	Vasculogenesis In Utero Embryonic Development Cardiac Muscle Fiber Development
Pathways		Hedgehog 'off' state
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrial fibrillation ( 30061737 29892015) Copper levels ( 26025379) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Mathematical ability in children with dyslexia ( 23423138) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Urate levels in lean individuals ( 25811787) Urinary calcium excretion ( 31993563)
Interacting Genes		63 interacting genes: ACTN2 AKAP9 ANKRD1 ANKRD54 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PRKAR1A PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23	4 interacting genes: ACTB PSMC5 SRPK2 TULP3
Entrez ID		7289	84700
HPRD ID		05292	09529
Ensembl ID		ENSG00000078246	ENSG00000133454
Uniprot IDs		B7Z1E7 O75386	Q8IUG5
PDB IDs
Enriched GO Terms of Interacting Partners?
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