TMEM218 and KCNJ6

Data Source:
BioGRID (two hybrid)

		TMEM218	KCNJ6
Description		transmembrane protein 218	potassium inwardly rectifying channel subfamily J member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Integral Component Of Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process		Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)	Body size at age 10 ( 32376654) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	63 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID		219854	3763
HPRD ID		19054	02929
Ensembl ID		ENSG00000150433	ENSG00000157542
Uniprot IDs		A2RU14	P48051
PDB IDs
Enriched GO Terms of Interacting Partners?
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