FARSA and COG4

Data Source:
BioGRID (two hybrid)

		FARSA	COG4
Description		phenylalanyl-tRNA synthetase subunit alpha	component of oligomeric golgi complex 4
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GO Annotations	Cellular Component	Cytoplasm Cytosol Phenylalanine-tRNA Ligase Complex Membrane	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	TRNA Binding RNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Protein Heterotetramerization	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization
Pathways		Cytosolic tRNA aminoacylation	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs		Phenylalanine
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Estimated glomerular filtration rate ( 31152163) Red blood cell count ( 27863252) Red blood cell traits ( 23222517) Type 2 diabetes ( 30297969)	Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		13 interacting genes: A2M ABI3 APOE COG4 ECSIT ESR1 FARSB GORAB HNRNPR PDCD10 PTEN RNF32 TDGF1	15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9
Entrez ID		2193	25839
HPRD ID		04227	08444
Ensembl ID		ENSG00000179115	ENSG00000103051
Uniprot IDs		Q6IBR2 Q9Y285	A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3
PDB IDs		3L4G	3HR0
Enriched GO Terms of Interacting Partners?
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