FARSA and HNRNPR

Data Source:
HPRD (two hybrid)

		FARSA	HNRNPR
Description		phenylalanyl-tRNA synthetase subunit alpha	heterogeneous nuclear ribonucleoprotein R
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GO Annotations	Cellular Component	Cytoplasm Cytosol Phenylalanine-tRNA Ligase Complex Membrane	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Endoplasmic Reticulum Dendrite Growth Cone Axon Terminus Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	TRNA Binding RNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Protein Heterotetramerization	MRNA Splicing, Via Spliceosome MRNA Processing Circadian Rhythm RNA Metabolic Process Negative Regulation Of Catalytic Activity MRNA Destabilization
Pathways		Cytosolic tRNA aminoacylation	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs		Phenylalanine
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Estimated glomerular filtration rate ( 31152163) Red blood cell count ( 27863252) Red blood cell traits ( 23222517) Type 2 diabetes ( 30297969)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		13 interacting genes: A2M ABI3 APOE COG4 ECSIT ESR1 FARSB GORAB HNRNPR PDCD10 PTEN RNF32 TDGF1	84 interacting genes: ANKRD28 BMPR2 FARSA H3-4 IL7R MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCDHB14 PRMT1 RASD1 RPL26 SMN1 SUMO2 TAB1
Entrez ID		2193	10236
HPRD ID		04227	06228
Ensembl ID		ENSG00000179115	ENSG00000125944
Uniprot IDs		Q6IBR2 Q9Y285	B4DMB1 B4DMD1 B4DT28 O43390 Q0VGD6 Q6MZS5
PDB IDs		3L4G	2DK2
Enriched GO Terms of Interacting Partners?
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