ZMYND11 and HOXD4

Data Source:
BioGRID (two hybrid)

		ZMYND11	HOXD4
Description		zinc finger MYND-type containing 11	homeobox D4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Chromatin Nucleus Nucleoplasm Cell Junction
	Molecular Function	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Malaria ( 31844061)	Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1	21 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 FANCL HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 PBX4 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18
Entrez ID		10771	3233
HPRD ID		09830	00864
Ensembl ID		ENSG00000015171	ENSG00000170166
Uniprot IDs		B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2	P09016
PDB IDs		4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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