ERCC1 and UHRF1

ERCC1

UHRF1

Description ERCC excision repair 1, endonuclease non-catalytic subunit ubiquitin like with PHD and ring finger domains 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Simvastatin-induced myopathy ( 31220337)
  • Birth weight ( 31043758)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Mental health study participation (completed survey) ( 31263887)
  • Systolic blood pressure ( 30578418)
  • Type 2 diabetes ( 30297969)
  • Urate levels ( 31578528)
Interacting Genes 18 interacting genes: APP CHRM5 ERCC4 GAS8 KIF11 MKRN3 RAD52 RPA1 RPA2 RPA3 SLX1A TRMT2B UBL7 UHRF1 USHBP1 USP45 VPS37B XPA 26 interacting genes: DNMT1 DNMT3A ERCC1 ERG FANCD2 H2AC4 H2BC3 H3-4 H3C1 H3C13 H3C14 H3C15 H4C14 KAT5 LASP1 LIG1 MBD4 MUS81 PCLAF PCNA PRKACA TP53 UBE2D1 UBE2D3 UBE2N UHRF2
Entrez ID 2067 29128
HPRD ID 00533 06992
Ensembl ID ENSG00000012061 ENSG00000276043
Uniprot IDs A0A024R0Q6 P07992 A0A087WVR3 Q96T88
PDB IDs 1Z00 2A1I 2A1J 2JNW 2JPD 2MUT 6SXA 6SXB 2FAZ 2L3R 2LGG 2LGK 2LGL 2PB7 3ASK 3ASL 3BI7 3CLZ 3DB3 3DB4 3DWH 3FL2 3SHB 3SOU 3SOW 3SOX 3T6R 3ZVY 3ZVZ 4GY5 4QQD 5C6D 5IAY 5XPI 5YY9 5YYA 6B9M 6IIW 6VCS 6VED
Enriched GO Terms of Interacting Partners?
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