EPS8 and MYO15A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EPS8	MYO15A
Description		epidermal growth factor receptor pathway substrate 8	myosin XVA
Image
GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Growth Cone Vesicle Stereocilium Ruffle Membrane Synapse Extracellular Exosome	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection
	Molecular Function	Actin Binding Protein Binding Small GTPase Binding Signaling Adaptor Activity	Microfilament Motor Activity Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Regulation Of Rho Protein Signal Transduction Dendritic Cell Migration Regulation Of Catalytic Activity Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility Positive Regulation Of Ruffle Assembly	Actin Filament Organization Sensory Perception Of Sound Vesicle Transport Along Actin Filament
Pathways
Drugs
Diseases			Deafness, autosomal recessive
GWAS		Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913)	Change in neurofilament light levels ( 31295725) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Schizophrenia ( 25056061) Serum folate levels ( 29953918)
Interacting Genes		61 interacting genes: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BORCS6 BYSL C19orf25 C6orf141 C8orf33 CASK CBL CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 ITSN2 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RCAN3 RFXAP RSPH14 RUNX1T1 SCRN3 SERPINA5 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XAGE2 XRCC6 ZZZ3	4 interacting genes: EPS8 FASLG USP13 WHRN
Entrez ID		2059	51168
HPRD ID		02563	04049
Ensembl ID		ENSG00000151491	ENSG00000091536
Uniprot IDs		B4E3T6 Q12929	Q9UKN7
PDB IDs		2E8M	6KZ1
Enriched GO Terms of Interacting Partners?
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