MUC20 and ALDOB

Data Source:
BioGRID (two hybrid)

		MUC20	ALDOB
Description		mucin 20, cell surface associated	aldolase, fructose-bisphosphate B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Golgi Lumen Plasma Membrane Basal Plasma Membrane Apical Plasma Membrane Microvillus Membrane	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome
	Molecular Function	Identical Protein Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding
	Biological Process	Activation Of MAPK Activity Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Hepatocyte Growth Factor Receptor Signaling Pathway	Fructose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Canonical Glycolysis Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family MET activates RAS signaling O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism
Drugs			1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate
Diseases			Hereditary fructose intolerance; Fructosemia
GWAS		Estimated glomerular filtration rate ( 31015462) Lung disease severity in cystic fibrosis ( 26417704)	Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 29403010)
Interacting Genes		3 interacting genes: ALDOB ELOVL3 MET	22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2
Entrez ID		200958	229
HPRD ID		17615	01972
Ensembl ID		ENSG00000176945	ENSG00000136872
Uniprot IDs		A0A0G2JN31 A0A0G2JR26 A0A0G2JSE2 Q8N307	A0A024R145 P05062
PDB IDs			1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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