LCE4A and VASN

Data Source:
BioGRID (two hybrid)

		LCE4A	VASN
Description		late cornified envelope 4A	vasorin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Cadherin Binding Transforming Growth Factor Beta Binding
	Biological Process	Keratinization	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Erectile dysfunction ( 30583798) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		69 interacting genes: ADAMTSL4 CRCT1 CREB5 CYSRT1 FUCA2 GRN HOXA1 HSD3B7 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1E LCE2B LCE2C LCE5A MDFI MEOX2 NBPF19 NOTCH2NLA OTX1 P4HB PLSCR1 PLSCR3 RGS17 RGS19 RGS20 RNF111 SLC39A7 SMCP SPRY1 SPRY2 TGM1 TRIM42 TSPAN4 VASN VWC2 ZNF655	53 interacting genes: ADAMTSL4 AQP3 CIB4 CYSRT1 GRN GUCD1 HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2C LCE2D LCE4A LNX1 MDFI MEOX2 MTUS2 NBPF19 NOTCH2NLA NR4A3 RGS17 RGS19 RGS20 RNF31 SMCP SSC4D TGFB1 TGFB2 TGFB3 TGM1 TRIP6 VWC2
Entrez ID		199834	114990
HPRD ID		17264	10587
Ensembl ID		ENSG00000187170	ENSG00000168140
Uniprot IDs		Q5TA78	Q6EMK4
PDB IDs
Enriched GO Terms of Interacting Partners?
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