ECE1 and AGT

  • Data Source:
  • BioGRID (enzymatic study)

ECE1

AGT

Description endothelin converting enzyme 1 angiotensinogen
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Coronary artery disease ( 29212778 33020668)
  • Diastolic blood pressure ( 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean arterial pressure ( 27618448)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Systolic blood pressure ( 27841878 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 14 interacting genes: AGT CALCA CLK1 CLK2 CYSRT1 EDN1 KNG1 KRTAP1-3 KRTAP10-1 KRTAP10-5 KRTAP10-8 MTDH MTNR1A MYOC 23 interacting genes: ACE2 AGTR1 AGTR2 ATP6AP2 CMA1 CTSG DNPEP ECE1 ENPEP EWSR1 GRB2 GSDMB ITSN2 KNG1 LNPEP MAS1 MEP1A MME PRCP PREP PRG2 REN TP53
Entrez ID 1889 183
HPRD ID 02690 00106
Ensembl ID ENSG00000117298 ENSG00000135744
Uniprot IDs A0A024RAB0 A0A024RAB2 A1PUP8 P42892 B0ZBE2 B2R5S1 P01019
PDB IDs 3DWB 1N9U 1N9V 2JP8 2WXW 2X0B 3CK0 3WOO 3WOR 4AA1 4APH 4FYS 5E2Q 5M3X 5M3Y 5XJM 6I3F 6I3I 6JOD 6OS0 7C6A
Enriched GO Terms of Interacting Partners?
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