ECE1

Description		endothelin converting enzyme 1
Image
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Plasma Membrane External Side Of Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Endosome Membrane Vesicle Weibel-Palade Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Endopeptidase Activity Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Peptide Hormone Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Receptor Recycling Regulation Of Systemic Arterial Blood Pressure By Endothelin Heart Development Substance P Catabolic Process Bradykinin Catabolic Process Calcitonin Catabolic Process Protein Processing Peptide Hormone Processing Regulation Of Vasoconstriction Endothelin Maturation Hormone Catabolic Process Embryonic Digit Morphogenesis Ear Development
Pathways		Peptide ligand-binding receptors
Drugs		5-(2-hydroxyethyl)nonane-1,9-diol
Diseases
GWAS		Body mass index ( 28552196) Body size at age 10 ( 32376654) Feeling worry ( 29500382) Height ( 25282103) Longevity (age >90th survival percentile) ( 31413261) Morning person ( 30696823) Obesity-related traits ( 23251661) Weight ( 28552196)
Novel Interacting Genes		1 novel interacting genes: CFLAR
Interacting Genes		14 interacting genes: AGT CALCA CLK1 CLK2 CYSRT1 EDN1 KNG1 KRTAP1-3 KRTAP10-1 KRTAP10-5 KRTAP10-8 MTDH MTNR1A MYOC
Entrez ID		1889
HPRD ID		02690
Ensembl ID		ENSG00000117298
Uniprot IDs		A0A024RAB0 A0A024RAB2 A1PUP8 P42892
PDB IDs		3DWB
Enriched GO Terms of Interacting Partners?
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