DSC1 and DSG1

Data Source:
BioGRID (pull down)

		DSC1	DSG1
Description		desmocollin 1	desmoglein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Gap Junction Membrane Integral Component Of Membrane Desmosome Extracellular Exosome Ficolin-1-rich Granule Membrane	Cornified Envelope Cytosol Plasma Membrane Cell-cell Junction Cytoplasmic Side Of Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Desmosome Ficolin-1-rich Granule Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Calcium Ion Binding Protein Binding Toxic Substance Binding Gamma-catenin Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Neutrophil Degranulation Cornification Cell-cell Adhesion	Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Keratinization Response To Progesterone Neutrophil Degranulation Protein Stabilization Maternal Process Involved In Female Pregnancy Cornification Cell-cell Adhesion
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs
Diseases			Striate palmoplantar keratoderma
GWAS		Multiple sclerosis ( 23412934)	Eosinophilic esophagitis (pediatric) ( 20208534) perceptual and visual search speed (trail making test A) (age interaction) ( 24629169) Yeast infection ( 28928442)
Interacting Genes		8 interacting genes: DSG1 DSG2 DSP JUP PKP1 PKP2 PKP3 UCHL5	8 interacting genes: CDC42 DSC1 DSC2 JUP KLK5 PKP1 PKP2 PKP3
Entrez ID		1823	1828
HPRD ID		00511	00515
Ensembl ID		ENSG00000134765	ENSG00000134760
Uniprot IDs		Q08554 Q9HB00	Q02413
PDB IDs		5IRY
Enriched GO Terms of Interacting Partners?
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