DNM2 and ATXN3

  • Data Source:
  • BioGRID (two hybrid)

DNM2

ATXN3

Description dynamin 2 ataxin 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793)
  • Coronary artery calcification ( 23870195)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Height ( 18391950 18391951)
  • LDL cholesterol levels x loop diuretics use interaction ( 31806883)
  • Orofacial clefts ( 22419666)
  • Refractive error ( 32231278)
Interacting Genes 68 interacting genes: AMPH AOC1 AP2A1 APP APPL1 ATF7IP ATXN3 BAG3 BIN1 CCDC90B CCR5 CCT7 CDK1 CTTN DDX39B DNM1 DYNC1I1 DYNLL1 EIF3L EPS15 FLAD1 FNBP1L GDF9 GOLGA2 GRAP2 GRB2 HCK HMGB1 ITSN1 KDR MAN1B1 MANEA MPHOSPH6 NTAQ1 PALS2 PDE6G PFN1 PPIB PRKAA2 PSTPIP1 PTK2 PYGM QARS1 RHOU RNF8 RPS2 RWDD2B SDCBP SEC23A SH3GL2 SH3GLB1 SH3RF1 SHANK1 SHANK2 SNAPIN SNX9 SPRY2 SRC TIAM2 TRAF4 TRIP10 TYK2 UBASH3A VAV1 WBP4 XIAP ZBTB16 ZFAND6 53 interacting genes: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 CAPN1 CAPN2 CASP1 CDKN1A CHEK1 CSNK2B DNM2 EWSR1 GABARAP GSK3B HDAC6 KAT2B MAP1LC3A MAP1LC3C MAP3K1 MKNK1 NCOR1 NEDD8 PHAF1 PICK1 PJA1 PRKN PSMD7 RAD23A RAD23B RFFL RPS6KA1 SMURF1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2L3 UBE2S UBE4B UBQLN1 USP21 VCP
Entrez ID 1785 4287
HPRD ID 03852 06131
Ensembl ID ENSG00000079805 ENSG00000066427
Uniprot IDs P50570 Q8N1K8 A0A0A0MS38 C9JQV6 P54252
PDB IDs 2YS1 1YZB 2AGA 2DOS 2JRI 2KLZ 4WTH 4YS9
Enriched GO Terms of Interacting Partners?
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