ATXN3 and CAPN2

  • Data Source:
  • BioGRID (enzymatic study, enzymatic study)

ATXN3

CAPN2

Description ataxin 3 calpain 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793)
  • Coronary artery calcification ( 23870195)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Height ( 18391950 18391951)
  • LDL cholesterol levels x loop diuretics use interaction ( 31806883)
  • Orofacial clefts ( 22419666)
  • Refractive error ( 32231278)
  • Blood protein levels ( 30072576 29875488)
  • Carotenoid levels (alpha-carotene) ( 28002826)
  • Febrile seizures (MMR vaccine-related) ( 25344690)
  • Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae) ( 33208821)
  • Waist circumference ( 31170924)
Interacting Genes 53 interacting genes: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 CAPN1 CAPN2 CASP1 CDKN1A CHEK1 CSNK2B DNM2 EWSR1 GABARAP GSK3B HDAC6 KAT2B MAP1LC3A MAP1LC3C MAP3K1 MKNK1 NCOR1 NEDD8 PHAF1 PICK1 PJA1 PRKN PSMD7 RAD23A RAD23B RFFL RPS6KA1 SMURF1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2L3 UBE2S UBE4B UBQLN1 USP21 VCP 23 interacting genes: ATG5 ATXN3 BCL2 BID CAPNS1 CAPNS2 CASP9 CDK5R1 DUX4 F2RL1 GAS2 GRK2 KNG1 MAPK1 MAPT MTDH NFKBIA NMT1 PBXIP1 PTPN1 PTPRN TNS1 ZFYVE21
Entrez ID 4287 824
HPRD ID 06131 00254
Ensembl ID ENSG00000066427 ENSG00000162909
Uniprot IDs A0A0A0MS38 C9JQV6 P54252 B4DN77 P17655 Q59EF6
PDB IDs 1YZB 2AGA 2DOS 2JRI 2KLZ 4WTH 4YS9 1KFU 1KFX 2NQA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?