DLG3 and EXOC7

Data Source:
BioGRID (pull down)

		DLG3	EXOC7
Description		discs large MAGUK scaffold protein 3	exocyst complex component 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Plasma Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	Protein Binding Kinase Binding Phosphatase Binding	Protein Binding
	Biological Process	MAPK Cascade Negative Regulation Of Cell Population Proliferation Embryo Development Negative Regulation Of Phosphatase Activity Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Protein Tyrosine Kinase Activity Receptor Localization To Synapse Cell-cell Adhesion Regulation Of NMDA Receptor Activity	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor NrCAM interactions Activation of Ca-permeable Kainate Receptor RAF/MAP kinase cascade Neurexins and neuroligins Neurexins and neuroligins Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Mean platelet volume ( 32888494)	Body size at age 10 ( 32376654)
Interacting Genes		48 interacting genes: ABCA1 ADGRL1 APC ATP2B4 CACNG2 CALM1 CNKSR2 CRIPT DHRS11 DLG1 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 EIF4H ERBB4 EXOC4 EXOC7 GDA GLS2 GRIK2 GRIN1 GRIN2A GRIN2B GRIN2C GUCY1A2 KCNA4 KCNJ12 KCNJ2 KDELR1 KHDRBS1 KIF1B LIN7A LRP2 MAPK12 NLGN1 NLGN2 NLGN3 OSBP2 PLEKHA2 PTK2B RPS8 SCN4A SCN5A SEMA4C SYNGAP1 VTN	37 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14
Entrez ID		1741	23265
HPRD ID		02177	16292
Ensembl ID		ENSG00000082458	ENSG00000182473
Uniprot IDs		Q59FY1 Q92796	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs		1UM7 2FE5 2I1N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?