FAM9B and RUBCN

Data Source:
BioGRID (two hybrid)

		FAM9B	RUBCN
Description		family with sequence similarity 9 member B	rubicon autophagy regulator
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleoplasm	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549 28869591) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 29146897 27182965) Metabolite levels ( 23823483)
Interacting Genes		142 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C16orf72 C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614 ZNF777	15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648
Entrez ID		171483	9711
HPRD ID		15955	11069
Ensembl ID		ENSG00000177138	ENSG00000145016
Uniprot IDs		A0A024RBV3 Q8IZU0	Q8N4U6 Q92622
PDB IDs			6WCW
Enriched GO Terms of Interacting Partners?
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