RUBCN and ZNF250

Data Source:
BioGRID (two hybrid)

		RUBCN	ZNF250
Description		rubicon autophagy regulator	zinc finger protein 250
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648	109 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC130 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 DPPA2 DRC3 DVL2 FAM124A FAM161A FDXACB1 FHL5 GAS8 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1
Entrez ID		9711	58500
HPRD ID		11069	15758
Ensembl ID		ENSG00000145016	ENSG00000196150
Uniprot IDs		Q8N4U6 Q92622	B3KNS9 P15622
PDB IDs		6WCW
Enriched GO Terms of Interacting Partners?
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