DEFB4A and KCNA3

Data Source:
BioGRID (pull down)

		DEFB4A	KCNA3
Description		defensin beta 4A	potassium voltage-gated channel subfamily A member 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Calyx Of Held Membrane Raft Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Protein Binding CCR6 Chemokine Receptor Binding Chemoattractant Activity	Voltage-gated Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity
	Biological Process	Chemotaxis Immune Response G Protein-coupled Receptor Signaling Pathway Antimicrobial Humoral Response Killing Of Cells Of Other Organism Defense Response To Bacterium Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Beta defensins Defensins	Voltage gated Potassium channels
Drugs			Enflurane Clofazimine Promethazine Miconazole Dalfampridine
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464)
Interacting Genes		3 interacting genes: CCR6 KCNA3 TLR4	10 interacting genes: BAX CAV1 CD3D DEFB4A DLG1 DLG4 DOLK IL16 KCNA1 KCNA2
Entrez ID		1673	3738
HPRD ID		03739	15937
Ensembl ID		ENSG00000171711	ENSG00000177272
Uniprot IDs		O15263	P22001
PDB IDs		1E4Q 1FD3 1FD4 1FQQ 6CS9	4BGC
Enriched GO Terms of Interacting Partners?
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