SYNE4 and SEC23B

Data Source:
BioGRID (two hybrid)

		SYNE4	SEC23B
Description		spectrin repeat containing nuclear envelope family member 4	SEC23 homolog B, COPII coat complex component
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Intracellular Protein Transport Positive Regulation Of GTPase Activity COPII-coated Vesicle Cargo Loading
Pathways
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS			Refractive error ( 32231278)
Interacting Genes		56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648	25 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 RIN1 SEC23A SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UGT1A1
Entrez ID		163183	10483
HPRD ID		08776	11543
Ensembl ID		ENSG00000181392	ENSG00000101310
Uniprot IDs		Q8N205	A0A2R8YFH5 Q15437
PDB IDs		6R16
Enriched GO Terms of Interacting Partners?
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