AK8 and ALKBH3

Data Source:
BioGRID (two hybrid)

		AK8	ALKBH3
Description		adenylate kinase 8	alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Axoneme Sperm Flagellum	Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding	Protein Binding Ferrous Iron Binding L-ascorbic Acid Binding DNA-N1-methyladenine Dioxygenase Activity RNA N1-methyladenosine Dioxygenase Activity
	Biological Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Ventricular System Development Nucleoside Monophosphate Phosphorylation	DNA Repair DNA Dealkylation Involved In DNA Repair Cell Population Proliferation Oxidative Single-stranded DNA Demethylation Oxidative Single-stranded RNA Demethylation
Pathways		Interconversion of nucleotide di- and triphosphates	ALKBH3 mediated reversal of alkylation damage
Drugs		Bis(Adenosine)-5'-Pentaphosphate	Ascorbic acid
Diseases
GWAS		Obesity-related traits ( 23251661)	Chronotype ( 30696823) Morning person ( 30696823)
Interacting Genes		16 interacting genes: ALKBH3 CCDC102B CDK18 CNTF DPY30 FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 SMG9 SYT17 UBE2Z ZMAT2	12 interacting genes: AK8 FBXO7 GLRX3 GOLGA2 IKZF1 LNX1 OTUD4 SRPK1 SRPK2 TRIM55 TRIM63 ZDHHC17
Entrez ID		158067	221120
HPRD ID		12991	16793
Ensembl ID		ENSG00000165695	ENSG00000166199
Uniprot IDs		Q96MA6	Q96Q83
PDB IDs			2IUW
Enriched GO Terms of Interacting Partners?
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