ANKRD46 and CLDN7

Data Source:
BioGRID (two hybrid)

		ANKRD46	CLDN7
Description		ankyrin repeat domain 46	claudin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane
	Molecular Function		Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process		Cell Adhesion Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Population Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Bicellular Tight Junction Assembly Positive Regulation Of Cell Motility
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)	Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		61 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A GOLM1 GPR152 GPR42 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2	77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MFSD5 MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1
Entrez ID		157567	1366
HPRD ID		14103	07633
Ensembl ID		ENSG00000186106	ENSG00000181885
Uniprot IDs		A0A024R9E1 A0A024R9G2 B3KT99 Q86W74	A0A384ME58 F5H496 O95471
PDB IDs
Enriched GO Terms of Interacting Partners?
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