CCDC167 and SERINC2

Data Source:
BioGRID (two hybrid)

		CCDC167	SERINC2
Description		coiled-coil domain containing 167	serine incorporator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding
	Biological Process		Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity
Pathways			Serine biosynthesis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Restless legs syndrome ( 29029846) Smoking status (ever vs never smokers) ( 30643258)	Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		42 interacting genes: APPBP2 AQP2 AQP6 AQP9 ARL13B CD79A CLDN5 CX3CR1 EBP ELOVL4 ERGIC3 FAM174A FAM210B FFAR2 GJA8 GLP1R GOLT1A GPR152 GPR42 HSD17B13 MS4A3 MTNR1A MUC1 NIPA1 OPRM1 RETREG3 SERINC2 SLC10A6 SLC18A3 SLC35C2 SLC7A14 SYT2 TACR1 TLCD4 TM4SF19 TMEM179B TMEM237 TMEM51 TMEM80 TMEM86B TMX2 VKORC1	16 interacting genes: C4orf3 CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B
Entrez ID		154467	347735
HPRD ID		18561	15481
Ensembl ID		ENSG00000198937	ENSG00000168528
Uniprot IDs		Q9P0B6	Q96IM8 Q96SA4
PDB IDs
Enriched GO Terms of Interacting Partners?
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