CCDC167 and SYT2

Data Source:
BioGRID (two hybrid)

		CCDC167	SYT2
Description		coiled-coil domain containing 167	synaptotagmin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Axon Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Chromaffin Granule Membrane Exocytic Vesicle
	Molecular Function	Protein Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Inositol 1,3,4,5 Tetrakisphosphate Binding
	Biological Process		Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Synaptic Vesicle Endocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Membrane Organization Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways			Toxicity of botulinum toxin type B (botB) Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			Botulinum Toxin Type B
Diseases
GWAS		Acne (severe) ( 24927181) Restless legs syndrome ( 29029846) Smoking status (ever vs never smokers) ( 30643258)	Celiac disease ( 23936387) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		42 interacting genes: APPBP2 AQP2 AQP6 AQP9 ARL13B CD79A CLDN5 CX3CR1 EBP ELOVL4 ERGIC3 FAM174A FAM210B FFAR2 GJA8 GLP1R GOLT1A GPR152 GPR42 HSD17B13 MS4A3 MTNR1A MUC1 NIPA1 OPRM1 RETREG3 SERINC2 SLC10A6 SLC18A3 SLC35C2 SLC7A14 SYT2 TACR1 TLCD4 TM4SF19 TMEM179B TMEM237 TMEM51 TMEM80 TMEM86B TMX2 VKORC1	29 interacting genes: AQP10 BNIP2 CCDC167 CLDN4 CMTM3 FA2H FUNDC2 ITGAM KLHL3 LAT MALL MIP NAPB NRXN1 ORMDL3 PLPP4 PMP22 SLC30A8 SLC35A1 SLC35A4 STON2 SYNCRIP TF THSD7B TMEM107 TMEM229B TSPO2 VAMP4 WNK1
Entrez ID		154467	127833
HPRD ID		18561	02520
Ensembl ID		ENSG00000198937	ENSG00000143858
Uniprot IDs		Q9P0B6	Q8N9I0
PDB IDs
Enriched GO Terms of Interacting Partners?
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