CYB561 and ORMDL2

Data Source:
BioGRID (two hybrid)

		CYB561	ORMDL2
Description		cytochrome b561	ORMDL sphingolipid biosynthesis regulator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Transport Vesicle Membrane	Endoplasmic Reticulum Integral Component Of Membrane SPOTS Complex
	Molecular Function	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding	Protein Binding
	Biological Process	Electron Transport Chain	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process
Pathways			Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)	Refractive error ( 32231278)
Interacting Genes		59 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35C2 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7	21 interacting genes: AQP6 CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 FAM210B FCER1G GJA8 KCNJ6 MMGT1 RETREG3 SCN3B SLC10A1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15
Entrez ID		1534	29095
HPRD ID		02485	17802
Ensembl ID		ENSG00000008283	ENSG00000123353
Uniprot IDs		B3KTA1 J3QRH5 P49447	Q53FV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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