CCDC13 and CCND3

Data Source:
BioGRID (two hybrid)

		CCDC13	CCND3
Description		coiled-coil domain containing 13	cyclin D3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Centriolar Satellite Cell Projection	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cytoplasmic Microtubule Organization Non-motile Cilium Assembly	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Phosphorylation Signal Transduction T Cell Proliferation Regulation Of Cell Population Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Insulin Receptor Signaling Pathway Cell Division Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Transcriptional regulation of white adipocyte differentiation MAPK6/MAPK4 signaling Cyclin D associated events in G1 Regulation of RUNX1 Expression and Activity Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Obesity-related traits ( 23251661) Periodontitis (DPAL) ( 24024966)	Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Cardiometabolic and hematological traits ( 27668658) Crohn's disease ( 28067908) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549 28334899) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hematological parameters ( 19820697) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin ( 29403010 32888494 28453575 20139978 27863252 28017375 19862010) Mean corpuscular hemoglobin concentration ( 32888494 28017375) Mean corpuscular volume ( 23263863 29403010 32888494 28453575 20139978 27863252 28017375 19862010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil count ( 21507922) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 29403010 32888494 20139978 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: ASB15 CARD9 CCDC120 CCDC136 CCHCR1 CCND3 CDR2 DISC1 EFHC2 EHHADH ENKD1 FAM161A FAM161B FAM221B FAM90A1 FCHO1 GMCL1 GOLGA2 HAP1 HOMEZ HSF2BP KIAA1328 KRT34 LZTS1 MCRS1 MEOX2 MYF5 NEFL OPTN PIBF1 PRDM16 RALBP1 RPSA TCHP TCL1A TFIP11 TP53BP2 TRAF3 TRIM23 TSGA10IP TXLNB USP54 VPS52 ZBED1 ZBTB22 ZBTB43 ZGPAT ZNF670 ZRANB1	56 interacting genes: AKAP8 APP AREG ATF5 ATP5F1C C14orf119 CASP2 CCDC13 CDK11B CDK14 CDK16 CDK18 CDK3 CDK4 CDK5 CDK6 CDKN1A CDKN1B CDKN2D CRABP2 DMRTB1 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS FHL3 GC HGS KIFC3 LSM3 MAF1 MAPK4 MAPK6 MCM10 MNS1 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL PSMC1 QKI RARA RB1 RBL2 RUNX1 SH3GLB2 SIL1 TEX11 TFIP11 TSG101 VDR
Entrez ID		152206	896
HPRD ID		08692	00452
Ensembl ID		ENSG00000244607	ENSG00000112576
Uniprot IDs		Q8IYE1 Q96LI1	B3KP19 D6RI00 P30281 Q5T8J1
PDB IDs			3G33
Enriched GO Terms of Interacting Partners?
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