PDZD2 and ADGRB1

Data Source:
BioGRID (unspecified method)

		PDZD2	ADGRB1
Description		PDZ domain containing 2	adhesion G protein-coupled receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Cell-cell Junction Centriolar Satellite Intracellular Membrane-bounded Organelle	Phagocytic Cup Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Integral Component Of Membrane Dendrite Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function		Lipopolysaccharide Binding Phosphatidylserine Binding G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding
	Biological Process	Cell Adhesion	Phagocytosis, Recognition Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Chronic obstructive pulmonary disease ( 29394082) Corpus callosum central volume ( 31530798) Height ( 28552196) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Myocardial infarction ( 26708285) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Renal cell carcinoma ( 23184150) Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284) Reticulocyte fraction of red cells ( 32888494) Self-reported childhood asthma in adult smokers ( 30373671) Vertical cup-disc ratio ( 31798171 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Working memory ( 31598132)
Interacting Genes		5 interacting genes: ADGRB1 CST3 CTNND2 NRXN1 PKP4	21 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 DRD2 ELMO1 ERBB2 GPR35 GPR37 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2
Entrez ID		23037	575
HPRD ID		10142	04062
Ensembl ID		ENSG00000133401	ENSG00000181790
Uniprot IDs		A0A024RE15 O15018	O14514
PDB IDs
Enriched GO Terms of Interacting Partners?
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