CCDC17 and KRT16

Data Source:
BioGRID (two hybrid)

		CCDC17	KRT16
Description		coiled-coil domain containing 17	keratin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process		Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 31562340) Hematocrit ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: BCAS2 FGFR3 GOLGA2 KRT16 KRT31 KRTAP19-5 KRTAP6-2 KRTAP8-1 MTUS2 N4BP3 TRIM54	56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1
Entrez ID		149483	3868
HPRD ID		08155	01018
Ensembl ID		ENSG00000159588	ENSG00000186832
Uniprot IDs		Q96LX7	P08779
PDB IDs
Enriched GO Terms of Interacting Partners?
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